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KMID : 1191520090140010075
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Journal of Korean Traditional Oncology
2009 Volume.14 No. 1 p.75 ~ p.84
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Study on the Anti-tumor Effect of Gekko
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Ahn Tae-Kyu
Son Chang-Gue
Jung Tae-Young
Yoo Hwa-Seung
Cho Jung-Hyo
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Abstract
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Gekko has been used for several diseases including cancer in Oriental medicine and fork herbalogy. Nevertheless, its origin as herbal medicine and its efficacy and mechanism as anti-tumor drug have not yet been thoroughly reported in Korea. This study aimed to investigate anti-tumor effect of Gekko through selected articles from cqvip database in China. In vitro and In vivo, Gekko could obviously inhibit tumor growth, induce tumor cells apoptosis, reduce micro-vessel density in tumor tissue through down regulating VEGF & bFGF protein expression, promote cytotoxicity of lymphocyte. Gekko could improve survival rate, relive clinical symptoms, improve quality of life, and relieve anti-tumor treatment reaction, suggesting that Gekko might be a effective anti-tumor drug.
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KEYWORD
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Gekko, Oriental medicine, Cancer, Anti-tumor
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